Flugal 150 Capsule | Fluconazole | Uses, Dosage, Interaction | ePharma
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Flugal 150mg Capsule

Generic: Fluconazole

Type: Capsule

Pack Size: 10 Pcs

Fluconazole 

  • Treats various fungal infections (such as systemic candidiasis, mucosal candidiasis, cryptococcosis, and vaginal candidiasis)
  • Prevents fungal infection in immunocompromised patients

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Discount Price: ৳ 208.68
MRP: ৳ 222 6% Off

⪼ Save  ৳: 13.32  in this Product


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✅ Description:

  • Flugal 150mg Capsule is primarily prescribed for treating hepatosplenic candidiasis, Candida infections, cryptococcal infections, and secondary prophylaxis for cryptococcal meningitis in AIDS patients. It belongs to the class of triazole antifungal drugs. Flugal 150mg Capsule is also used to treat fungal infections in various parts of the body, including the mouth, throat, lungs, and vagina.
  • It works by inhibiting the production of ergosterol, a substance necessary for fungal cell membrane formation. This medication is used as a preventive measure in patients susceptible to fungal infections during chemotherapy, radiation therapy, and bone marrow transplantation.
  • Some serious side effects may occur and require immediate medical attention, such as liver damage (indicated by yellowing of the skin, dark urine, etc.), severe skin rash, irregular heart rate, seizures, or fainting.
  • To ensure effective treatment, take Flugal 150mg Capsule as directed, follow good hygiene practices to prevent reinfection, and undergo frequent blood tests if required. Adequate hydration is essential unless otherwise instructed. In case of an overdose, seek medical assistance promptly.

Safety Advices


Alcohol
UNSAFE

Avoid excess alcohol while taking Flugal 150mg Capsule, as alcohol may worsen the side effects like dizziness.


Pregnancy
CONSULT YOUR DOCTOR

Flugal 150mg Capsule is not recommended for use during pregnancy unless considered clearly necessary. Consult your doctor before taking Flugal 150mg Capsule.


Breastfeeding
CONSULT YOUR DOCTOR

Flugal 150mg Capsule is not recommended for use in breastfeeding women after repeated use or after a high dose of this medicine. You may continue breastfeeding after a single dose of Flugal 150mg Capsule. Consult your doctor before taking Flugal 150mg Capsule.


Driving
CAUTION

Do not drive or operate any machines if you experience dizziness or fits after taking Flugal 150mg Capsule.


Kidney
CONSULT YOUR DOCTOR

Flugal 150mg Capsule should be used with caution in patients with kidney dysfunction. Consult your doctor before taking Flugal 150mg Capsule.


Liver
CONSULT YOUR DOCTOR

Flugal 150mg Capsule should be used with caution in patients with liver dysfunction. Consult your doctor before taking Flugal 150mg Capsule.

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✔️ Uses of Flugal 150mg Capsule
  • Treat fungal infections.
✔️ How does Flugal 150mg Capsule work?

Flugal 150mg Capsule works by stopping the growth of fungus and preventing the spread of infection.

✔️ Side Effects of Flugal 150mg Capsule
  • Headache
  • Nausea and vomiting
  • Stomach pain
  • Diarrhea
  • Indigestion
  • Hair loss
  • Heartburn
  • Swelling of face, lips, eyelids, tongue, hands and feet
  • Dizziness
  • Drowsiness
✔️ Quick Suggestions:
  • Flugal 150mg Capsule is used to treat various fungal infections such as candida infection.
  • You should not take this medicine if you are allergic to fluconazole or other similar antifungal medication.
  • Take this medicine as prescribed by your doctor at a fixed time to gain optimal benefits.
  • Always complete the entire course of the treatment with Flugal 150mg Capsule, as incomplete treatment may result in treatment failure and an increased risk of re-infection.
  • This medicine should not be used by pregnant women unless needed or in case of a life-threatening infection.
  • Diarrhea, nausea, vomiting, headache, and skin rashes can be seen as side effects of this medicine. Inform your doctor if the side effects do not resolve over time.
  • Talk to your doctor if you are allergic to fluconazole or any other ingredient of it.
✔️ Indication of Flugal 150mg Capsule

Flugal 150mg Capsule is used to treat various fungal infections in different parts of the body, including:

  • Oropharyngeal candidiasis - fungal infection in the mouth and throat.
  • Oesophageal candidiasis - fungal infection in the food pipe (esophagus).
  • Cryptococcal meningitis - serious infection affecting the membranes covering the brain and spinal cord.
  • Vaginal candidiasis - fungal infection in the vagina causing pain, itching, and unusual discharge.
  • Fungal urinary tract infection - infection in the urinary system caused by Candida species.
  • Peritonitis - swelling of the peritoneum due to bacteria or fungi.
  • Candidemia - a fungal infection of the blood caused by Candida species.
  • Prophylaxis of Infections in Special Population - used to prevent fungal infections in people receiving chemotherapy or bone marrow transplantation.
  • Fungal Pneumonia - fungal infection affecting the lungs.
  • Skin fungal infections (Dermatomycosis) - mild to moderate fungal infections of the skin, hair, and nails.
  • fungal infections of the skin, hair, and nails.

Flugal 150mg Capsule works by inhibiting the production of ergosterol, which is essential for fungal cell membrane formation. It is an effective treatment for these various fungal infections.

✔️ Pharmacology

Fluconazole is a triazole antifungal that is used to treat fungal infections. It's a strong inhibitor of cytochrome P-450-dependent enzymes in fungi. The ergosterol synthesis is carried out by the Cytochrome P-450 enzyme system, which is an important component of the fungal cell membrane.

✔️ Dosage & Administration of Flugal 150mg Capsule

For adults with different fungal infections, the recommended oral doses of Flugal 150mg Capsule are as follows:

  1. Vaginal candidiasis: 150 mg as a single dose.
  2. Oropharyngeal candidiasis: 200 mg on the first day, followed by 100 mg once daily. Continue treatment for at least 2 weeks to reduce the chance of relapse.
  3. Esophageal candidiasis: 200 mg on the first day, followed by 100 mg once daily. Doses up to 400 mg/day may be used. Treat for a minimum of three weeks and at least two weeks after symptom resolution.
  4. Systemic candida infections: Optimal dosage and duration have not been established, but doses of up to 400 mg daily have been used.
  5. Urinary tract infections and peritonitis caused by candida: 50-200 mg daily.
  6. Cryptococcal meningitis: 400 mg on the first day, followed by 200 mg once daily.
  7. Prophylaxis for bone marrow transplantation patients: 400 mg once daily.

For children, the recommended oral dose is 3-6 mg/kg daily, with doses up to 12 mg/kg recommended. Take Flugal 150mg Capsule as prescribed by your physician, with a glass of water, without chewing or crushing the medicine. The doctor will determine the correct dose and duration based on your age, body weight, and type of infection.

✔️ Interaction
  • Terfenadine, Voriconazole, Clarithromycin, Erythromycin, Ranolazine, Lomitapide, Donepezil, Pimozide, Quinidine: Never take Fluconazole with these medicines, as it can cause a life-threatening heart rhythm condition (torsades de pointes).
  • Anesthetic medicines like Alfentanil, and Fentanyl: When used with Flugal 150mg Capsule, the effect of these medicines is increased, leading to increased side effects.
  • Medicines for psychotic disorders like Amitriptyline, and Nortriptyline: Concomitant use with Flugal 150mg Capsule increases the effects of these medicines, resulting in more side effects.
  • Blood thinners like Warfarin: Concomitant use with Flugal 150mg Capsule may increase the risk of bleeding.
  • Medicines for psychotic disorders like Benzodiazepines (Midazolam, Triazolam): The effect of these medicines is increased when used together with Flugal 150mg Capsule, leading to increased side effects.
  • Medicines to treat fits like Phenytoin, Carbamazepine: The effect of these medicines is increased on concomitant use with Flugal 150mg Capsule, which can increase the side effects of phenytoin.
  • Medicines used for treating cancer (Olaparib, Vinca alkaloids) and preventing organ transplant rejection (Ciclosporin): The effect of these medicines is increased when used together with Flugal 150mg Capsule.
  • Medicines for reducing high cholesterol levels like Atorvastatin: When used together with Flugal 150mg Capsule, there may be an increased risk of muscle weakness (Myopathy).
  • Medicines for treating pain and inflammation like Ibuprofen: The side effects associated with these medicines, such as ulcers, increase when used together with Flugal 150mg Capsule.
  • Contraceptive pills: The effect of contraceptive pills might be reduced when used with a Flugal 150mg Capsule. Additional barrier contraception is needed.
  • Medicines to control asthma-like Theophylline: When used together with Flugal 150mg Capsule, the side effects associated with Theophylline may increase.
  • Medicines to treat irregular heartbeats like Amiodarone: There is an increased risk of heart-related side effects when Flugal 150mg Capsule is used together with these medicines.
  • Antidiabetic medicines like Chlorpropamide, Glibenclamide: The effect of these medicines is increased, leading to lower blood glucose levels when used together with Flugal 150mg Capsule.
✔️ Contraindications
  • If you are allergic to fluconazole or any other ingredient of Flugal 150mg Capsule.
  • If you are taking medicines like Astemizole, Terfenadine, Cisapride, Pimozide, Quinidine, Erythromycin.
✔️ Pregnancy & Lactation

Fluconazole is classified as a category C drug by the US Food and Drug Administration (FDA) for use during pregnancy. Fluconazole should thus be avoided during pregnancy and breastfeeding unless the potential advantages outweigh the potential hazards to the baby.

✔️ Precautions & Warnings
  • Before using Flugal 150mg Capsule, inform your doctor about all the prescription and non-prescription medicines, as well as vitamin and herbal supplements you are taking. If you are allergic to Flugal 150mg Capsule or any of its components, do not use this medicine. Let your doctor know if you have any liver, kidney, or heart problems before starting Flugal 150mg Capsule.
  • This medicine may not be suitable for some people with a weakened immune system, diabetes, cancer, or low blood magnesium or potassium levels. If you fall under any of these categories, seek medical advice before using Flugal 150mg Capsule.
  • Pregnant or lactating women should consult their doctor before taking Flugal 150mg Capsule.
  • If you experience dizziness or other side effects that may affect your mental ability to drive, do not drive or operate machinery.
  • Avoid alcohol consumption along with Flugal 150mg Capsule to avoid undesirable effects
✔️ Storage Conditions

Do not store Flugal 150mg Capsule above 25°C. Keep out of the reach of children and pets.

Frequently Asked Questions (FAQ)

Flugal 150mg Capsuleshould be used with caution in elderly patients, particularly with renal impairment. Your doctor may adjust the dose depending on kidney function. Consult your doctor for advice before taking Flugal 150mg Capsule.

Common side effects of Flugal 150mg Capsule include headache, nausea, vomiting, diarrhea, abdominal pain, indigestion, and acne. Consult your doctor if any of these symptoms worsen or do not improve over time.

If you miss a dose of Flugal 150mg Capsule, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take the next scheduled dose. Do not double the dose to make up for the missed one as this may increase the chances of developing side effects.

The onset of action of Flugal 150mg Capsule is not known after administration, but its effects may last in your body for approximately 7-8 days.

Stay cautious while using Flugal 150mg Capsule if you have a weakened immune system, diabetes, cancer, or low blood magnesium or potassium levels. It is advised to seek a doctor's advice before starting Flugal 150mg Capsule if you have a previous medical history.

The usual recommendation for Flugal 150mg Capsule is to be used for a short time. However, your doctor may prescribe it for a longer time, depending on the type and severity of your infection.

Do not stop using Flugal 150mg Capsule even if you feel better until the doctor's advised course is finished. Your symptoms may improve before the infection is completely cured.

Flugal 150mg Capsule contains Fluconazole, an antifungal drug that works by killing the fungus/yeast and preventing its growth by inhibiting the fungal cell membrane formation, thereby treating fungal infections.
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Disclaimer:
ePharma sole intention is to ensure that its consumers get proper information as musch as possible. Although we do not guarantee the accuracy and the completeness of the information that provided and here information is for informational purposes only. The information contained herein should NOT be used as a substitute for the advice of a qualified physician. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your healthcare professional and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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